Pmetrics - Pmetrics for Population Modeling and Simulation
Pmetrics is short for pharmacometrics, the discipline of modeling drug kinetics and effects on biologic systems, including disease progression. Models can be used to simulate novel therapeutic dosing regimens and/or populations, informing trial design and dosing strategies. The package supports primarily non-parametric but also parametric pharmacometric modeling and simulation with functions to run and analyze the output from all three components of the Pmetrics software suite for population pharmacometric data analysis: 1) IT2B (Iterative Two-Stage Bayesian) for parametric models; 2) NPAG (Non-parametric Adaptive Grid) for non-paramametric models; 3) Simulator for semi-parametric Monte-Carlo simulations.
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modelingpharmacokineticssimulationrustcargo
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